The Transatlantic Information Exchange System (TIESWeb) was conceived by a group of European and American Ngo leaders and academics, led by Franck Biancheri, founder and current president of the organization, at a conference organized by the European Union and the United States in Washington, D.C. in 1997 as part of the New Transatlantic Agenda.

At "Bridging the Atlantic - People to People Conference," EU President Jacques Santer and U.S. President Bill Clinton agreed that greater communication should occur between citizens to facilitate transatlantic relations. A network of sponsors that included USIA, the European Commission, the European Parliament, and the Dutch Government provided resources to create TIESWeb. The mission of the organization has been to strengthen the transatlantic partnership by promoting dialogue between individuals on a people-to-people level. This dialogue is for the purpose of deepening the processes that support a liberal, democratic society.

The framework of TIESWeb was developed at a conference held in Amsterdam during 1997. At that time, it was determined that TIESWeb would be an Internet-based portal built around sections that correspond directly to key issues involved in transatlantic collaboration. The sections would be designed to provide information to promote transatlantic communication. A demo of TIESWeb was displayed to European and US leaders at Blair House, at the occasion of the December 1997 EU/US summit in Washington DC.

The proto-type of the TIESWeb site was revealed at a public demonstration in London during 1998. The TIESWeb portal was officially introduced on January 1, 1999 and evaluated at a conference open to the general public later that month in Atlanta. The first year generated a great deal of interest with an average of 30,000 "hits" per month.

In 2001, a new organisation, called TIESWEB was set up, supported by Transatlantic Information Exchange System, gathering new partners in order to develop the more ambitious TIESWeb site with aims not only to link citizens across the Atlantic but also to address key issues at the core of future EU/US relations. The mission of TIESWeb continued to expand at a conference in Miami in 2001 where it was decided that a more proactive agenda was needed to energize civil society linkages on a transatlantic basis.

The result was a major conference in Miami in 2002 (co-sponsored by Hippocrene Foundation and Robert Bosch Foundation , NGOs, medias and the State of Florida) where a "Civil Society Agenda" was defined for improving transatlantic cooperation. This agenda marks a transition in TIESWeb to an organization dedicated to forming a network through which civil society influences the transatlantic process into a mutually rewarding collaboration. In 2004, the second edition of the Transatlantic Congress took place in Miami, as well. For three days, a hundred participants and speakers coming from throughout the USA and the European Union, and also from Middle East and Africa, have gathered into the superb location of Miami Children’s Museum in order to discuss four key topics: Atlantic Rim, Middle East 2020, International Education, Transatlantic Leadership. Those brainstorming seminars were then concluded by a large conference hosted by Barry University which put together hundreds of Miami students and a series of keynote speakers from EU and USA.

The latest TIESWEB worldwide event is currently taking place : the Transatlantic Citizen Marathon -TCM, Franck Biancheri, the marathonian, is going to the US for a month and is holding several series of debates, a succession of 3 tours in 15 different states : -the North East Tour (NET); -the South-East & North Tour (SENT); -the Middle & West Tour (in October MWT). These conferences aim at trying to bridge the current political and cultural gap between the U.S. and the E.U. He will set out to speak and network with Americans in order to help determine the future of transatlantic relations.